Representative Investments*
Zerigo Health, Inc.
Zerigo Health offers the only comprehensive, clinically proven, at-home solution that seamlessly connects people with chronic skin conditions and providers to deliver optimal dermatological outcomes. Zerigo's precision solution is FDA-cleared for use on all skin types and remotely treats and monitors people with chronic skin conditions using narrowband ultraviolet B (NB-UVB) phototherapy, a proven, standard-of-care treatment. People benefit from the unique combination of advanced technology with personal coaching and support throughout their treatment journey, which results in documented increases in treatment adherence and patient satisfaction. The name Zerigo is derived from the primary disorders the company’s solution treats: eczema, psoriasis and vitiligo. These conditions affect over 30 million people in the U.S.
Equinox
Equinox is a medical device company with an adjustable, non-surgical, non-pharmacological technology to treat diseases of the optic nerve such as glaucoma, idiopathic intracranial hypertension (IIH), hypotony, visual impairment and intracranial pressure (VIIP). The company has been granted two patents with four patents in process. It has also received early funding commitments from leading ophthalmology experts, and a grant from NASA/NSBRI as part of the Vision For Mars program.
Orasis Pharmaceuticals
Orasis Pharmaceuticals developed Qlosi™, an FDA approved corrective eye drop for the treatment of presbyopia in adults. Presbyopia is the gradual loss of an eye’s ability to focus on near objects, which begins to affect most people sometime after the age of 40 and affects more than 1.8 billion people worldwide. Orasis is led by a collaborative team of industry executives and eye care professionals with a broad range of experiences in research, development, and commercialization of pharmaceutical drugs, as well as finance and business development. Orasis is funded by a diverse group of sophisticated and experienced life science and healthcare investors.
Continental Realty Group / CRA
This Denver, Colorado based company has been in the business of acquiring, renovating, owning, operating, and selling multi-family housing complexes nationwide for more than 25 years. Their proprietary system, AIM, allows them to manage the phases of the real estate investment process: Analysis-Investment-Management. Because of their track record and unique due diligence process, Bluestem has participated in a number of investments with this company and has invested in many properties in high growth markets.
VIRUN, INC.
VIRUN, a Nutra-BioSciences® company, has developed over 200 fortified ingredients and finished beverage and supplement products; with over 60 patents and patent applications world-wide, focused on difficult-to-dissolve variants for food, beverage and supplement applications. The ingredients are associated with health claims, such as: Cardiovascular Health, Energy and Cognitive Function, Weight Management, and Energy. VIRUN has successfully branded its OmegaH2O® Omega-3 EPA DHA, Coenzyme Clear® CoQ10, Esolv®, and DPtechnology® among other water soluble liquid and powder concentrates.
EDCO
EDCO Health Information Solutions designs, develops and implements software solutions for the health care industry in North America. EDCO’s Solarity® software provides point of care batch scanning and indexing of patient medical records that complements electronic health record systems. The end result is an accurate and complete electronic medical record, reduced costs, and improved patient outcomes. For more information visit http://www.solaritybyedco.com/
neurolens™, Inc. (formerly eyeBrain Medical)
Inspired by a breakthrough discovery linking optometry and neurology, neurolens is unlocking a new dimension of vision care. With patented Contoured Prism technology, neurolenses are the first and only prescription lenses that go beyond visual acuity to provide visual comfort for the nearly 65% of US adults who complain of headaches, neck/shoulder pain and eyestrain when using digital devices, reading or doing detail work. The neurolens Contoured Prism design helps the eyes work together comfortably, bringing the eyes into alignment to relieve painful symptoms. Technology from neurolens is only available to Independent Eye Care Providers.
Virtual Incision Corporation
Virtual Incision is on a mission to simplify robotic-assisted surgery (RAS), so more patients and their surgeons can access its benefits every day. Headquartered in Lincoln, Nebraska, and holding over two hundred patents and patent applications, the company is developing MIRA, the first-of-its-kind miniature RAS system. Virtual Incision’s goal is to make every operating room RAS-ready.
The Prairie Club
The Prairie Club (Destination Golf, LLC) is a semi-private golf resort located in the secluded sandhills of Nebraska, along the edge of the Snake River canyon. Built in 2009 with two distinct 18-hole courses, a unique 10-hole par three course, and a 40,000 square foot lodge, The Prairie Club was quickly received as one of the best in the world, with Links Magazine naming it one of the top ten 36-hole resorts in North America. Today, it has expanded its on-site lodging to 71 rooms, boasts a growing membership of over 400, and attracts avid golfers from all over the world.
ianTECH
ianTECH delivers a minimally invasive micro-interventional device to treat cataracts in safe and cost-effective manner without heat-generating vibrational energy or expensive electrically powered equipment.
SYNQ3
This company, founded in 2007, specializes in operational and off-premise efficiencies for managing incoming calls for its restaurant industry customers. For the company’s fifteen national and regional customers, all phone-in-orders or catering calls from around the U.S. are handled at the Colorado Springs, CO headquarters. VIA, their Virtual Intelligent Assistant, enables measurement of guest experience, guest engagement, and order to-call ratios—metrics formerly unmeasurable in the restaurant industry.
SpringCM
SpringCM is a secure document and contract management platform. Build workflows and enable document collaboration across your entire organization. Because when your documents flow, work flows.
Surface Pharmaceuticals
A biopharmaceutical company focused on development and commercialization of innovative therapeutics for ocular diseases.
Hitch Works Inc.
Hitch is a cloud-based skills intelligence and internal talent mobility platform that helps companies become more inclusive, adaptive, and innovative by connecting the right talent with the right tasks based on skills, experiences and career aspirations. Its proprietary AI-powered solution enables upskilling and reskilling, dynamic teaming, democratized career development, and fosters a culture of learning and growth while accelerating productivity and performance.
POET
POET, one of the world's largest ethanol producers, is a leader in biorefining through its efficient, vertically integrated approach to production. The 25-year-old company has a production capacity in excess of 1.6 billion gallons of ethanol and 9 billion pounds of high-protein animal feed annually from its network of 27 production facilities. POET also operates a pilot-scale cellulosic bio-ethanol plant, which uses corn cobs, leaves, husk and some stalk as feedstock, and expects to commercialize the process in Emmetsburg, Iowa through its joint venture with DSM.
TearClear
TearClear Corp. is an early-stage, disruptive eye health technology company focused on developing a safe and reliable means of delivering preservative-free topical ophthalmic drugs from existing preserved, multi-dose systems.
LENTECHS
LENTECHS, LLC is a privately held, clinical-stage ophthalmic medical device company, focused on developing a new generation of soft, suspended contact lenses. Headquartered in Columbus, Ohio, LENTECHS is backed by a network of investors who are truly committed to revolutionary innovation in contact lenses.
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sight4all, Inc.
OcuDoc, Inc. is a medical diagnostic company based in Columbus, Ohio. The company’s mission is to identify and assist people globally who suffer from impaired vision (including eye misalignment and refractive errors) with an accessible, accurate and low-cost solution.
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Tear Film Innovations
Tear Film Innovations is an early-stage company developing a family of break-through products for the treatment of evaporative dry eye and related syndromes including meibomian gland dysfunction (MGD) and blepharitis
Sydnexis, Inc.
Founded in 2014, Sydnexis is a privately held, pre-commercial biopharmaceutical company focused on decreasing the progression of myopia in children. Myopia currently affects 28 million children in the U.S. Sydnexis recently completed its three-year primary endpoint in a pivotal Phase 3 clinical trial evaluating its proprietary low-dose atropine formulation to slow progression of pediatric myopia and the risk of associated co-morbidities. The Phase 3 clinical trial is now completing the fourth-year randomized withdrawal for exploratory endpoints and third year results will be announced upon completion of the fourth year of the study. The company is venture-backed by four major investors: RA Capital, Longitude Capital, Visionary Ventures, and Bluestem Capital.
Shoulder Innovations, Inc.
Shoulder Innovations Inc., based in Holland, Mich., is a medical device development company that designs and commercializes innovative products which demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Leveraging its breakthrough, patented, InSet™ glenoid design, Shoulder Innovations is commercializing a shoulder replacement implant system focused on improving outcomes related to the greatest cause of shoulder replacement failure: glenoid loosening. The InSet™ technology has been shown in multiple peer reviewed publications to significantly reduce glenoid implant micro-motion and simplifies the surgical technique, potentially reducing complications or increasing implant longevity.
Pivotal Health Solutions
Pivotal Health Solutions, based in Watertown, SD, manufactures and sells products into the chiropractic, massage, therapy, spa and medical industries. Their trusted brands include: Eurotech Tables, ErgoStyle Tables, iTrac Therapy Chair, Custom Craftworks, Touch Essentials, Cloud 9 Medical Gel, SaniCover, VTI Products, Valley Technology, Lyflo Select, Hydrajoint, Relax Right Memory Foam Pillows, OMNI Cervical Relief Pillows and Apollo Cold Laser. The Company also has partnered with Pressure Positive and Teeter.
The Community Company
The Community Company builds and manages community-driven programs for media companies and global brands.